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Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

Arp2/3-branched actin is critical for cytoskeletal dynamics and cell migration. However, perturbations and diseases affecting this network have phenotypes that cannot be fully explained by cell-autonomous effects. In this paper, we report nonautonomous effects of Arp2/3 depletion. We show that, upon...

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Detalles Bibliográficos
Autores principales: Wu, Congying, Haynes, Elizabeth M., Asokan, Sreeja B., Simon, Jeremy M., Sharpless, Norman E., Baldwin, Albert S., Davis, Ian J., Johnson, Gary L., Bear, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871425/
https://www.ncbi.nlm.nih.gov/pubmed/24344184
http://dx.doi.org/10.1083/jcb.201306032