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Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling
Arp2/3-branched actin is critical for cytoskeletal dynamics and cell migration. However, perturbations and diseases affecting this network have phenotypes that cannot be fully explained by cell-autonomous effects. In this paper, we report nonautonomous effects of Arp2/3 depletion. We show that, upon...
Autores principales: | Wu, Congying, Haynes, Elizabeth M., Asokan, Sreeja B., Simon, Jeremy M., Sharpless, Norman E., Baldwin, Albert S., Davis, Ian J., Johnson, Gary L., Bear, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871425/ https://www.ncbi.nlm.nih.gov/pubmed/24344184 http://dx.doi.org/10.1083/jcb.201306032 |
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