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Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

Control of lipid droplet (LD) nucleation and copy number are critical, yet poorly understood, processes. We use model peptides that shift from the endoplasmic reticulum (ER) to LDs in response to fatty acids to characterize the initial steps of LD formation occurring in lipid-starved cells. Initiall...

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Detalles Bibliográficos
Autores principales: Kassan, Adam, Herms, Albert, Fernández-Vidal, Andrea, Bosch, Marta, Schieber, Nicole L., Reddy, Babu J.N., Fajardo, Alba, Gelabert-Baldrich, Mariona, Tebar, Francesc, Enrich, Carlos, Gross, Steven P., Parton, Robert G., Pol, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871434/
https://www.ncbi.nlm.nih.gov/pubmed/24368806
http://dx.doi.org/10.1083/jcb.201305142