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Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
Control of lipid droplet (LD) nucleation and copy number are critical, yet poorly understood, processes. We use model peptides that shift from the endoplasmic reticulum (ER) to LDs in response to fatty acids to characterize the initial steps of LD formation occurring in lipid-starved cells. Initiall...
Autores principales: | Kassan, Adam, Herms, Albert, Fernández-Vidal, Andrea, Bosch, Marta, Schieber, Nicole L., Reddy, Babu J.N., Fajardo, Alba, Gelabert-Baldrich, Mariona, Tebar, Francesc, Enrich, Carlos, Gross, Steven P., Parton, Robert G., Pol, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871434/ https://www.ncbi.nlm.nih.gov/pubmed/24368806 http://dx.doi.org/10.1083/jcb.201305142 |
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