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KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity

Aurora B kinase phosphorylates kinetochore proteins during early mitosis, increasing kinetochore–microtubule (MT) turnover and preventing premature stabilization of kinetochore–MT attachments. Phosphorylation of kinetochore proteins during late mitosis is low, promoting attachment stabilization, whi...

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Detalles Bibliográficos
Autores principales: Caldas, Gina V., DeLuca, Keith F., DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871439/
https://www.ncbi.nlm.nih.gov/pubmed/24344188
http://dx.doi.org/10.1083/jcb.201306054