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KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity
Aurora B kinase phosphorylates kinetochore proteins during early mitosis, increasing kinetochore–microtubule (MT) turnover and preventing premature stabilization of kinetochore–MT attachments. Phosphorylation of kinetochore proteins during late mitosis is low, promoting attachment stabilization, whi...
Autores principales: | Caldas, Gina V., DeLuca, Keith F., DeLuca, Jennifer G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871439/ https://www.ncbi.nlm.nih.gov/pubmed/24344188 http://dx.doi.org/10.1083/jcb.201306054 |
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