Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules

Septin 9 (SEPT9) interacts with microtubules (MTs) and is mutated in hereditary neuralgic amyotrophy (HNA), an autosomal-dominant neuropathy. The mechanism of SEPT9 interaction with MTs and the molecular basis of HNA are unknown. Here, we show that the N-terminal domain of SEPT9 contains the novel r...

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Detalles Bibliográficos
Autores principales: Bai, Xiaobo, Bowen, Jonathan R., Knox, Tara K., Zhou, Kaifeng, Pendziwiat, Manuela, Kuhlenbäumer, Gregor, Sindelar, Charles V., Spiliotis, Elias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871440/
https://www.ncbi.nlm.nih.gov/pubmed/24344182
http://dx.doi.org/10.1083/jcb.201308068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871440/
https://www.ncbi.nlm.nih.gov/pubmed/24344182
http://dx.doi.org/10.1083/jcb.201308068

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