JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation

Lymphocyte recruitment is regulated by signaling modules based on the activity of Rho and Rap small guanosine triphosphatases that control integrin activation by chemokines. We show that Janus kinase (JAK) protein tyrosine kinases control chemokine-induced LFA-1– and VLA-4–mediated adhesion as well...

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Detalles Bibliográficos
Autores principales: Montresor, Alessio, Bolomini-Vittori, Matteo, Toffali, Lara, Rossi, Barbara, Constantin, Gabriela, Laudanna, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871442/
https://www.ncbi.nlm.nih.gov/pubmed/24368807
http://dx.doi.org/10.1083/jcb.201303067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871442/
https://www.ncbi.nlm.nih.gov/pubmed/24368807
http://dx.doi.org/10.1083/jcb.201303067

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