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Lysine deacetylase inhibition promotes relaxation of arterial tone and C-terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells

There is increasing interest in establishing the roles that lysine acetylation of non nuclear proteins may exert in modulating cell function. Lysine deacetylase 8 (KDAC8), for example, has been suggested to interact with α-actin and control the differentiation of smooth muscle cells. However, a dire...

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Detalles Bibliográficos
Autores principales: Chen, Aiqing, Karolczak-Bayatti, Magdalena, Sweeney, Michèle, Treumann, Achim, Morrissey, Kelly, Ulrich, Scott M, Nicholas Europe-Finner, G, Taggart, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871448/
https://www.ncbi.nlm.nih.gov/pubmed/24400135
http://dx.doi.org/10.1002/phy2.127