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Mycophenolate mofetil prevents high-fat diet–induced hypertension and renal glomerular injury in Dahl SS rats

We designed experiments to test the hypothesis that Dahl salt-sensitive (SS) rats are sensitive to high-fat diet (HFD)–induced hypertension and renal injury via an inflammatory mechanism. Twelve-week-old Dahl SS rats were maintained on a normal diet (ND; 14% fat), HFD (59% fat), or HFD supplemented...

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Detalles Bibliográficos
Autores principales: Spradley, Frank T, De Miguel, Carmen, Hobbs, Janet, Pollock, David M, Pollock, Jennifer S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871452/
https://www.ncbi.nlm.nih.gov/pubmed/24400139
http://dx.doi.org/10.1002/phy2.137