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Concurrent muscle and bone deterioration in a murine model of cancer cachexia

Cachexia is defined as an excessive, involuntary loss of fat and lean tissue. We tested the validity of the Lewis lung carcinoma (LLC) as a model of cancer cachexia and examined its effect on the two major lean tissue components, skeletal muscle and bone. LLC cells (0.75 × 10(6)) were injected into...

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Detalles Bibliográficos
Autores principales: Choi, EunHi, Carruthers, Kadir, Zhang, Li, Thomas, Nathan, Battaglino, Ricardo A, Morse, Leslie R, Widrick, Jeffrey J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871459/
https://www.ncbi.nlm.nih.gov/pubmed/24400146
http://dx.doi.org/10.1002/phy2.144