Maternal-to-fetal allopurinol transfer and xanthine oxidase suppression in the late gestation pregnant rat

Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an inhibitor of the prooxidant enzyme xanthine oxidase. Here, we established in a rodent model the cap...

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Detalles Bibliográficos
Autores principales: Kane, Andrew D, Camm, Emily J, Richter, Hans G, Lusby, Ciara, Tijsseling, Deodata, Kaandorp, Joepe J, Derks, Jan B, Ozanne, Susan E, Giussani, Dino A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871471/
https://www.ncbi.nlm.nih.gov/pubmed/24400158
http://dx.doi.org/10.1002/phy2.156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871471/
https://www.ncbi.nlm.nih.gov/pubmed/24400158
http://dx.doi.org/10.1002/phy2.156

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