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Maternal-to-fetal allopurinol transfer and xanthine oxidase suppression in the late gestation pregnant rat
Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an inhibitor of the prooxidant enzyme xanthine oxidase. Here, we established in a rodent model the cap...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871471/ https://www.ncbi.nlm.nih.gov/pubmed/24400158 http://dx.doi.org/10.1002/phy2.156 |