Orexin A Affects INS-1 Rat Insulinoma Cell Proliferation via Orexin Receptor 1 and the AKT Signaling Pathway

Our aim is to investigate the role of the AKT/PKB (protein kinase B) signaling pathway acting via orexin receptor 1 (OX1R) and the effects of orexin A (OXA) on cell proliferation in the insulin-secreting beta-cell line (INS-1 cells). Rat INS-1 cells were exposed to different concentrations of OXA in...

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Detalles Bibliográficos
Autores principales: Chen, Li, Zhao, Yuyan, Zheng, Delu, Ju, Shujing, Shen, Yang, Guo, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871501/
https://www.ncbi.nlm.nih.gov/pubmed/24382962
http://dx.doi.org/10.1155/2013/854623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871501/
https://www.ncbi.nlm.nih.gov/pubmed/24382962
http://dx.doi.org/10.1155/2013/854623

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