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Correlation of N-Acetyltransferase 2 Genotype with Isoniazid Acetylation in Polish Tuberculosis Patients

Isoniazid (INH), a key agent in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. Patients treated with INH can be classified as fast, intermediate, and slow acetylators. The objective of this study was to explore the rel...

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Detalles Bibliográficos
Autores principales: Zabost, Anna, Brzezińska, Sylwia, Kozińska, Monika, Błachnio, Maria, Jagodziński, Jacek, Zwolska, Zofia, Augustynowicz-Kopeć, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871508/
https://www.ncbi.nlm.nih.gov/pubmed/24383060
http://dx.doi.org/10.1155/2013/853602