Cargando…

Correlation of N-Acetyltransferase 2 Genotype with Isoniazid Acetylation in Polish Tuberculosis Patients

Isoniazid (INH), a key agent in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. Patients treated with INH can be classified as fast, intermediate, and slow acetylators. The objective of this study was to explore the rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zabost, Anna, Brzezińska, Sylwia, Kozińska, Monika, Błachnio, Maria, Jagodziński, Jacek, Zwolska, Zofia, Augustynowicz-Kopeć, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871508/ https://www.ncbi.nlm.nih.gov/pubmed/24383060 http://dx.doi.org/10.1155/2013/853602

Ejemplares similares

Molecular methods in diagnostics of post-BCG vaccine adverse events
por: BRZEZIŃSKA, SYLWIA AGATA, et al.
Publicado: (2020)

Tuberculosis in Poland: Epidemiological and Molecular Analysis during the COVID-19 Pandemic
por: Borkowska-Tatar, Dagmara, et al.
Publicado: (2022)

COVID-19 in Patients with Active Tuberculosis
por: Kozińska, Monika, et al.
Publicado: (2021)

Mutations in the embB Gene and Their Association with Ethambutol Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates from Poland
por: Bakuła, Zofia, et al.
Publicado: (2013)

Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin
por: Zaczek, Anna, et al.
Publicado: (2009)

Use of a FluoroType(®) System for the Rapid Detection of Patients with Multidrug-Resistant Tuberculosis—State of the Art Case Presentations
por: Zabost, Anna, et al.
Publicado: (2022)

An overview of tuberculosis outbreaks reported in the years 2011–2020
por: Żukowska, Lidia, et al.
Publicado: (2023)

Screening for Streptomycin Resistance-Conferring Mutations in Mycobacterium tuberculosis Clinical Isolates from Poland
por: Jagielski, Tomasz, et al.
Publicado: (2014)

Epidemiological characterization of Mycobacterium caprae strains isolated from wildlife in the Bieszczady Mountains, on the border of Southeast Poland
por: Orłowska, Blanka, et al.
Publicado: (2020)

Correction: An overview of Tuberculosis outbreaks reported in the years 2011–2020
por: Żukowska, Lidia, et al.
Publicado: (2023)

Mycobacterium chimaera as an Underestimated Cause of NTM Lung Diseases in Patients Hospitalized in Pulmonary Wards
por: ZABOST, ANNA T., et al.
Publicado: (2021)

Multidrug-Resistant Tuberculosis—Diagnostic Procedures and Treatment of Two Beijing-like TB Cases
por: Kozińska, Monika, et al.
Publicado: (2022)

Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes
por: Doll, Mark A., et al.
Publicado: (2017)

Correlation of N-acetyltransferase 2 genotype and acetylation status with plasma isoniazid concentration and its metabolic ratio in ethiopian tuberculosis patients
por: Sileshi, Tesemma, et al.
Publicado: (2023)

Mycobacterial Interspersed Repeat Unit–Variable Number Tandem Repeat Typing of Mycobacterium avium Strains Isolated from the Lymph Nodes of Free-Living Carnivorous Animals in Poland
por: Orłowska, Blanka, et al.
Publicado: (2023)

N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment
por: Mthiyane, Thuli, et al.
Publicado: (2020)

Mycobacterium bovis Transmission between Cattle and a Farmer in Central Poland
por: Krajewska-Wędzina, Monika, et al.
Publicado: (2022)

Evaluation of Susceptibility to Antimycobacterial Drugs in Mycobacterium Tuberculosis Complex Strains Isolated from Cattle in Poland
por: Krajewska-Wędzina, Monika, et al.
Publicado: (2017)

Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
por: Kozińska, Monika, et al.
Publicado: (2023)

Cutaneous tuberculosis—ambiguous transmission, bacterial diversity with biofilm formation in humoral abnormality: case report illustration
por: Zdziarski, Przemysław, et al.
Publicado: (2023)

Molecular Characterisation of the Mycobacterium Bovis Causing Bovine Tuberculosis Outbreaks in Poland
por: Krajewska-Wędzina, Monika, et al.
Publicado: (2020)

Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
por: Gobis, Katarzyna, et al.
Publicado: (2011)

N-acetyltransferase gene polymorphisms & plasma isoniazid concentrations in patients with tuberculosis
por: Hemanth Kumar, A. K., et al.
Publicado: (2017)

Is Serological Monitoring a Fit-for-purpose Tool to Assess the Epidemiological Situation of Tuberculosis in the Sylvatic Species of European Bison (Bison Bonasus) in Poland?
por: Krzysiak, Michał K., et al.
Publicado: (2022)

The role of Mycobacterium tuberculosis acetyltransferase and protein acetylation modifications in tuberculosis
por: Huang, Yinxia, et al.
Publicado: (2023)

Mycobacterial Infections in Invasive Turtle Species in Poland
por: Radulski, Łukasz, et al.
Publicado: (2023)

New RAPMYCOI Sensititre(TM) Antimicrobial Susceptibility Test for Atypical Rapidly Growing Mycobacteria (RGM)
por: Borek, Anna, et al.
Publicado: (2022)

Improved genotyping of N-acetyltransferase 2: role of the ultra-slow acetylators
por: Blaszkewicz, Meinolf
Publicado: (2013)

Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2
por: Hong, Kyung U., et al.
Publicado: (2020)

From NTM (Nontuberculous mycobacterium) to Gordonia bronchialis—A Diagnostic Challenge in the COPD Patient
por: Franczuk, Monika, et al.
Publicado: (2022)

XDR-TB Transmitted from Mother to 10-Month-Old Infant: Diagnostic and Therapeutic Problems
por: Kozińska, Monika, et al.
Publicado: (2022)

Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis
por: Unissa, Ameeruddin Nusrath, et al.
Publicado: (2011)

Influence of N-acetyltransferase 2 (NAT2) genotype/single nucleotide polymorphisms on clearance of isoniazid in tuberculosis patients: a systematic review of population pharmacokinetic models
por: Thomas, Levin, et al.
Publicado: (2022)

Mycobacterium avium Subspecies paratuberculosis in Asymptomatic Zoo Herbivores in Poland
por: Bruczyńska, Małgorzata, et al.
Publicado: (2023)

QuantiFERON-TB Gold Plus Test in Diagnostics of Latent Tuberculosis Infection in Children Aged 1–14 in a Country with a Low Tuberculosis Incidence
por: BORKOWSKA-TATAR, DAGMARA, et al.
Publicado: (2021)

MIRU-VNTR Typing of Atypical Mycobacteria Isolated from the Lymph Nodes of Slaughtered Pigs from Poland
por: Majchrzak, Marta, et al.
Publicado: (2022)

Portable Surface Plasmon Resonance Detector for COVID-19 Infection
por: Trzaskowski, Maciej, et al.
Publicado: (2023)

Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients
por: Toure, A., et al.
Publicado: (2016)

The Role of N-Acetyl Transferases on Isoniazid Resistance from Mycobacterium tuberculosis and Human: An In Silico Approach
por: Unissa, Ameeruddin Nusrath, et al.
Publicado: (2017)

Isoniazid acetylation phenotypes in the Sudanese population; findings and implications
por: Ali, Monadil H., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_or6j7qdo1ngq2pbfjghlhijaol