Cilengitide-Induced Temporal Variations in Transvascular Transfer Parameters of Tumor Vasculature in a Rat Glioma Model: Identifying Potential MRI Biomarkers of Acute Effects

Increased efficacy of radiotherapy (RT) 4-8 h after Cilengitide treatment has been reported. We hypothesized that the effects of Cilengitide on tumor transvascular transfer parameters might underlie, and thus predict, this potentiation. Athymic rats with orthotopic U251 glioma were studied at ~21 da...

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Detalles Bibliográficos
Autores principales: Nagaraja, Tavarekere N., Aryal, Madhava P., Brown, Stephen L., Bagher-Ebadian, Hassan, Mikkelsen, Tom, Yang, James J., Panda, Swayamprava, Keenan, Kelly A., Cabral, Glauber, Ewing, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871527/
https://www.ncbi.nlm.nih.gov/pubmed/24376814
http://dx.doi.org/10.1371/journal.pone.0084493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871527/
https://www.ncbi.nlm.nih.gov/pubmed/24376814
http://dx.doi.org/10.1371/journal.pone.0084493

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