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At a Supra-Physiological Concentration, Human Sexual Hormones Act as Quorum-Sensing Inhibitors

N-Acylhomoserine lactone (AHL)-mediated quorum-sensing (QS) regulates virulence functions in plant and animal pathogens such as Agrobacterium tumefaciens and Pseudomonas aeruginosa. A chemolibrary of more than 3500 compounds was screened using two bacterial AHL-biosensors to identify QS-inhibitors (...

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Detalles Bibliográficos
Autores principales: Beury-Cirou, Amélie, Tannières, Mélanie, Minard, Corinne, Soulère, Laurent, Rasamiravaka, Tsiry, Dodd, Robert H., Queneau, Yves, Dessaux, Yves, Guillou, Catherine, Vandeputte, Olivier M., Faure, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871529/
https://www.ncbi.nlm.nih.gov/pubmed/24376718
http://dx.doi.org/10.1371/journal.pone.0083564