Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages

Oxidation of low-density lipoprotein (LDL) is one of the major causative mechanisms in the development of atherosclerosis. In previous studies, we showed that minimally oxidized LDL (mmLDL) induced inflammatory responses in macrophages, macropinocytosis and intracellular lipid accumulation and that...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Soo-Ho, Yin, Huiyong, Ravandi, Amir, Armando, Aaron, Dumlao, Darren, Kim, Jungsu, Almazan, Felicidad, Taylor, Angela M., McNamara, Coleen A., Tsimikas, Sotirios, Dennis, Edward A., Witztum, Joseph L., Miller, Yury I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871536/
https://www.ncbi.nlm.nih.gov/pubmed/24376657
http://dx.doi.org/10.1371/journal.pone.0083145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871536/
https://www.ncbi.nlm.nih.gov/pubmed/24376657
http://dx.doi.org/10.1371/journal.pone.0083145

Ejemplares similares