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Proteome-Wide Screening Reveals Immunodominance in the CD8 T Cell Response against Classical Swine Fever Virus with Antigen-Specificity Dependent on MHC Class I Haplotype Expression

Vaccination with live attenuated classical swine fever virus (CSFV) vaccines induces a rapid onset of protection which has been associated with virus-specific CD8 T cell IFN-γ responses. In this study, we assessed the specificity of this response, by screening a peptide library spanning the CSFV C-s...

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Detalles Bibliográficos
Autores principales: Franzoni, Giulia, Kurkure, Nitin V., Essler, Sabine E., Pedrera, Miriam, Everett, Helen E., Bodman-Smith, Kikki B., Crooke, Helen R., Graham, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871537/
https://www.ncbi.nlm.nih.gov/pubmed/24376799
http://dx.doi.org/10.1371/journal.pone.0084246