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Proteome-Wide Screening Reveals Immunodominance in the CD8 T Cell Response against Classical Swine Fever Virus with Antigen-Specificity Dependent on MHC Class I Haplotype Expression
Vaccination with live attenuated classical swine fever virus (CSFV) vaccines induces a rapid onset of protection which has been associated with virus-specific CD8 T cell IFN-γ responses. In this study, we assessed the specificity of this response, by screening a peptide library spanning the CSFV C-s...
Autores principales: | Franzoni, Giulia, Kurkure, Nitin V., Essler, Sabine E., Pedrera, Miriam, Everett, Helen E., Bodman-Smith, Kikki B., Crooke, Helen R., Graham, Simon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871537/ https://www.ncbi.nlm.nih.gov/pubmed/24376799 http://dx.doi.org/10.1371/journal.pone.0084246 |
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