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Functional Limitations of Plasmacytoid Dendritic Cells Limit Type I Interferon, T Cell Responses and Virus Control in Early Life

Infant mortality from viral infection remains a major global health concern: viruses causing acute infections in immunologically mature hosts often follow a more severe course in early life, with prolonged or persistent viral replication. Similarly, the WE strain of lymphocytic choriomeningitis viru...

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Detalles Bibliográficos
Autores principales: Belnoue, Elodie, Fontannaz, Paola, Rochat, Anne-Françoise, Tougne, Chantal, Bergthaler, Andreas, Lambert, Paul-Henri, Pinschewer, Daniel D., Siegrist, Claire-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871569/
https://www.ncbi.nlm.nih.gov/pubmed/24376875
http://dx.doi.org/10.1371/journal.pone.0085302