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Bisgma Stimulates Prostaglandin E2 Production in Macrophages via Cyclooxygenase-2, Cytosolic Phospholipase A2, and Mitogen-Activated Protein Kinases Family

BACKGROUND: Bisphenol A-glycidyl-methacrylate (BisGMA) employs as a monomer in dental resins. The leakage of BisGMA from composite resins into the peripheral environment can result in inflammation via macrophage activation. Prostaglandin E2 (PGE2) is a key regulator of immunopathology in inflammator...

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Detalles Bibliográficos
Autores principales: Kuan, Yu-Hsiang, Huang, Fu-Mei, Lee, Shiuan-Shinn, Li, Yi-Ching, Chang, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871582/
https://www.ncbi.nlm.nih.gov/pubmed/24376609
http://dx.doi.org/10.1371/journal.pone.0082942