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Autophagy Adaptor Protein p62/SQSTM1 and Autophagy-Related Gene Atg5 Mediate Autophagosome Formation in Response to Mycobacterium tuberculosis Infection in Dendritic Cells

Mycobacterium tuberculosis is an intracellular pathogen that can survive within phagocytic cells by inhibiting phagolysosome biogenesis. However, host cells can control the intracellular M. tuberculosis burden by the induction of autophagy. The mechanism of autophagosome formation to M. tuberculosis...

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Detalles Bibliográficos
Autores principales: Seto, Shintaro, Tsujimura, Kunio, Horii, Toshinobu, Koide, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871604/
https://www.ncbi.nlm.nih.gov/pubmed/24376899
http://dx.doi.org/10.1371/journal.pone.0086017