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Role of Electrical Activity in Horizontal Axon Growth in the Developing Cortex: A Time-Lapse Study Using Optogenetic Stimulation

During development, layer 2/3 neurons in the neocortex extend their axons horizontally, within the same layers, and stop growing at appropriate locations to form branches and synaptic connections. Firing and synaptic activity are thought to be involved in this process, but how neuronal activity regu...

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Detalles Bibliográficos
Autores principales: Malyshevskaya, Olga, Shiraishi, Yoshihiro, Kimura, Fumitaka, Yamamoto, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871609/
https://www.ncbi.nlm.nih.gov/pubmed/24376616
http://dx.doi.org/10.1371/journal.pone.0082954