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Role of Electrical Activity in Horizontal Axon Growth in the Developing Cortex: A Time-Lapse Study Using Optogenetic Stimulation
During development, layer 2/3 neurons in the neocortex extend their axons horizontally, within the same layers, and stop growing at appropriate locations to form branches and synaptic connections. Firing and synaptic activity are thought to be involved in this process, but how neuronal activity regu...
Autores principales: | Malyshevskaya, Olga, Shiraishi, Yoshihiro, Kimura, Fumitaka, Yamamoto, Nobuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871609/ https://www.ncbi.nlm.nih.gov/pubmed/24376616 http://dx.doi.org/10.1371/journal.pone.0082954 |
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