High Frequency Stimulation of the Subthalamic Nucleus Leads to Presynaptic GABA(B)-Dependent Depression of Subthalamo-Nigral Afferents

Patients with akinesia benefit from chronic high frequency stimulation (HFS) of the subthalamic nucleus (STN). Among the mechanisms contributing to the therapeutic success of HFS-STN might be a suppression of activity in the output region of the basal ganglia. Indeed, recordings in the substantia ni...

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Detalles Bibliográficos
Autores principales: Dvorzhak, Anton, Gertler, Christoph, Harnack, Daniel, Grantyn, Rosemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871646/
https://www.ncbi.nlm.nih.gov/pubmed/24376521
http://dx.doi.org/10.1371/journal.pone.0082191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871646/
https://www.ncbi.nlm.nih.gov/pubmed/24376521
http://dx.doi.org/10.1371/journal.pone.0082191

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