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High Frequency Stimulation of the Subthalamic Nucleus Leads to Presynaptic GABA(B)-Dependent Depression of Subthalamo-Nigral Afferents
Patients with akinesia benefit from chronic high frequency stimulation (HFS) of the subthalamic nucleus (STN). Among the mechanisms contributing to the therapeutic success of HFS-STN might be a suppression of activity in the output region of the basal ganglia. Indeed, recordings in the substantia ni...
Autores principales: | Dvorzhak, Anton, Gertler, Christoph, Harnack, Daniel, Grantyn, Rosemarie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871646/ https://www.ncbi.nlm.nih.gov/pubmed/24376521 http://dx.doi.org/10.1371/journal.pone.0082191 |
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