Molecular Crowding Inhibits U-Insertion/Deletion RNA Editing In Vitro: Consequences for the In Vivo Reaction

Mitochondrial pre-mRNAs in African trypanosomes are edited to generate functional transcripts. The reaction is typified by the insertion and deletion of U nucleotides and is catalyzed by a macromolecular complex, the editosome. Editosomes bind pre-edited mRNA/gRNA pairs and the reaction can be recap...

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Detalles Bibliográficos
Autores principales: Katari, Venkata Subbaraju, van Esdonk, Lea, Göringer, H. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871654/
https://www.ncbi.nlm.nih.gov/pubmed/24376749
http://dx.doi.org/10.1371/journal.pone.0083796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871654/
https://www.ncbi.nlm.nih.gov/pubmed/24376749
http://dx.doi.org/10.1371/journal.pone.0083796

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