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Human CD4+CD25+ Regulatory T Cells Are Sensitive to Low Dose Cyclophosphamide: Implications for the Immune Response

Regulatory T cells (Treg) play a pivotal role in the immune system since they inhibit the T cell response. It is well known that cyclophosphamide applied at low dose is able to stimulate the immune response while high dose cyclophosphamide exerts inhibitory activity. Data obtained in mice indicate t...

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Detalles Bibliográficos
Autores principales: Heylmann, Daniel, Bauer, Martina, Becker, Huong, van Gool, Stefaan, Bacher, Nicole, Steinbrink, Kerstin, Kaina, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871695/
https://www.ncbi.nlm.nih.gov/pubmed/24376696
http://dx.doi.org/10.1371/journal.pone.0083384