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Comparative Efficacy and Safety of Deferoxamine, Deferiprone and Deferasirox on Severe Thalassemia: A Meta-Analysis of 16 Randomized Controlled Trials

OBJECTIVE: A meta-analysis was conducted to investigate the efficacy and safety of three main iron chelators, namely, deferoxamine (DFO), deferiprone (DFP) and deferasirox (DFX) for thalassemia major (TM) patients. METHODS: Randomized controlled trials comparing mono-therapy DFO, DFP, DFX and combin...

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Detalles Bibliográficos
Autores principales: Xia, Sujian, Zhang, Weidong, Huang, Liting, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871701/
https://www.ncbi.nlm.nih.gov/pubmed/24376563
http://dx.doi.org/10.1371/journal.pone.0082662