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Counting RAD51 proteins disassembling from nucleoprotein filaments under tension

The central catalyst in eukaryotic ATP-dependent homologous recombination consists of RAD51 proteins, polymerized around single-stranded DNA. This nucleoprotein filament recognizes a homologous duplex DNA segment and invades it(1,2). After strand exchange, the nucleoprotein filament should disassemb...

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Detalles Bibliográficos
Autores principales: van Mameren, Joost, Modesti, Mauro, Kanaar, Roland, Wyman, Claire, Peterman, Erwin J. G., Wuite, Gijs J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871861/
https://www.ncbi.nlm.nih.gov/pubmed/19060884
http://dx.doi.org/10.1038/nature07581