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Volume Determination with Two Standards Allows Absolute Quantification and Improved Chemometric Analysis of Metabolites by NMR from Submicroliter Samples

[Image: see text] The accurate measurement of metabolite concentrations in miniscule biological sample volumes is often desirable, yet it remains challenging. In many cases, the starting analyte volumes are imprecisely known, or not directly measurable, and hence absolute metabolite concentrations a...

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Detalles Bibliográficos
Autores principales: Ragan, Timothy J., Bailey, Andrew P., Gould, Alex P., Driscoll, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871890/
https://www.ncbi.nlm.nih.gov/pubmed/24251761
http://dx.doi.org/10.1021/ac403111s