Strategies for Molecularly Enhanced Chemotherapy to Achieve Synthetic Lethality in Endometrial Tumors with Mutant p53

Serous uterine endometrial carcinomas are aggressive type II cancers with poor outcomes for which new treatment strategies are urgently needed, in particular, strategies that augment sensitivity to established chemotherapy regimens. The tumor suppressor gene TP53 is dysregulated in more than 90% of...

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Detalles Bibliográficos
Autores principales: Meng, Xiangbing, Dizon, Don S., Yang, Shujie, Wang, Xinjun, Zhu, Danlin, Thiel, Kristina W., Leslie, Kimberly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871910/
https://www.ncbi.nlm.nih.gov/pubmed/24381593
http://dx.doi.org/10.1155/2013/828165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871910/
https://www.ncbi.nlm.nih.gov/pubmed/24381593
http://dx.doi.org/10.1155/2013/828165

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