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l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice

Rationale: Diabetic nephropathy (DN) is a major cause of end-stage renal disease, associated with endothelial dysfunction. Chronic supplementation of l-arginine (l-arg), the substrate for endothelial nitric oxide synthase (eNOS), failed to improve vascular function. l-Citrulline (l-cit) supplementat...

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Detalles Bibliográficos
Autores principales: Romero, Maritza J., Yao, Lin, Sridhar, Supriya, Bhatta, Anil, Dou, Huijuan, Ramesh, Ganesan, Brands, Michael W., Pollock, David M., Caldwell, Ruth B., Cederbaum, Stephen D., Head, C. Alvin, Bagi, Zsolt, Lucas, Rudolf, Caldwell, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871963/
https://www.ncbi.nlm.nih.gov/pubmed/24400007
http://dx.doi.org/10.3389/fimmu.2013.00480