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The Anticonvulsant Enaminone E139 Attenuates Paclitaxel-Induced Neuropathic Pain in Rodents

The enaminone methyl 4-(4′-bromophenyl)aminocyclohex-3-en-6-methyl-2-oxo-1-oate (E139) has anticonvulsant activities. It has been reported to have a better safety profile than some anticonvulsant drugs. Since some anticonvulsant drugs are used in the management of neuropathic pain, we evaluated the...

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Detalles Bibliográficos
Autores principales: Thangamani, Dhandapani, Edafiogho, Ivan Ogheneochuko, Masocha, Willias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872104/
https://www.ncbi.nlm.nih.gov/pubmed/24385872
http://dx.doi.org/10.1155/2013/240508