Genetics of Adverse Reactions to Haloperidol in a Mouse Diallel: A Drug–Placebo Experiment and Bayesian Causal Analysis

Haloperidol is an efficacious antipsychotic drug that has serious, unpredictable motor side effects that limit its utility and cause noncompliance in many patients. Using a drug–placebo diallel of the eight founder strains of the Collaborative Cross and their F(1) hybrids, we characterized aggregate...

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Detalles Bibliográficos
Autores principales: Crowley, James J., Kim, Yunjung, Lenarcic, Alan B., Quackenbush, Corey R., Barrick, Cordelia J., Adkins, Daniel E., Shaw, Ginger S., Miller, Darla R., de Villena, Fernando Pardo-Manuel, Sullivan, Patrick F., Valdar, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872195/
https://www.ncbi.nlm.nih.gov/pubmed/24240528
http://dx.doi.org/10.1534/genetics.113.156901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872195/
https://www.ncbi.nlm.nih.gov/pubmed/24240528
http://dx.doi.org/10.1534/genetics.113.156901

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