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Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy

During mild stressful conditions, cells activate a multitude of mechanisms in an attempt to repair or re-establish homeostasis. One such mechanism is autophagic degradation of mitochondria or mitophagy to dispose damaged mitochondria. However, if stress persists beyond recovery then dysfunctional mi...

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Detalles Bibliográficos
Autores principales: Sureshbabu, Angara, Bhandari, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872744/
https://www.ncbi.nlm.nih.gov/pubmed/24421769
http://dx.doi.org/10.3389/fphys.2013.00384