Cargando…

A Mathematical Model of Immune Activation with a Unified Self-Nonself Concept

The adaptive immune system reacts against pathogenic nonself, whereas it normally remains tolerant to self. The initiation of an immune response requires a critical antigen(Ag)-stimulation and a critical number of Ag-specific T cells. Autoreactive T cells are not completely deleted by thymic selecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Khailaie, Sahamoddin, Bahrami, Fariba, Janahmadi, Mahyar, Milanez-Almeida, Pedro, Huehn, Jochen, Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872974/
https://www.ncbi.nlm.nih.gov/pubmed/24409179
http://dx.doi.org/10.3389/fimmu.2013.00474