The MTHFR C677T polymorphism and global DNA methylation in oral epithelial cells

DNA methylation is mediated by DNA methyltransferases (DNMTs) that add a methyl group to the 5′-carbon of cytosine. The enzyme methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the rate-limiting step of the cycle invo...

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Detalles Bibliográficos
Autores principales: de Arruda, Isabela Tatiana Sales, Persuhn, Darlene Camati, de Oliveira, Naila Francis Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2013
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873177/
https://www.ncbi.nlm.nih.gov/pubmed/24385849
http://dx.doi.org/10.1590/S1415-47572013005000035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873177/
https://www.ncbi.nlm.nih.gov/pubmed/24385849
http://dx.doi.org/10.1590/S1415-47572013005000035

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