Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson’s disease model

Understanding the mechanism(s) by which dopaminergic (DAergic) neurons are eroded in Parkinson’s disease (PD) is critical for effective therapeutic strategies. By using the binary tyrosine hydroxylase (TH)-Gal4/UAS-X RNAi Drosophila melanogaster system, we report that Dmp53, basket and drICE gene kn...

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Detalles Bibliográficos
Autores principales: Ortega-Arellano, Hector Flavio, Jimenez-Del-Rio, Marlene, Velez-Pardo, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2013
Materias:
Cellular, Molecular and Developmental Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873193/
https://www.ncbi.nlm.nih.gov/pubmed/24385865
http://dx.doi.org/10.1590/S1415-47572013000400020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873193/
https://www.ncbi.nlm.nih.gov/pubmed/24385865
http://dx.doi.org/10.1590/S1415-47572013000400020

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