Low Frequency Variants, Collapsed Based on Biological Knowledge, Uncover Complexity of Population Stratification in 1000 Genomes Project Data

Analyses investigating low frequency variants have the potential for explaining additional genetic heritability of many complex human traits. However, the natural frequencies of rare variation between human populations strongly confound genetic analyses. We have applied a novel collapsing method to...

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Detalles Bibliográficos
Autores principales: Moore, Carrie B., Wallace, John R., Wolfe, Daniel J., Frase, Alex T., Pendergrass, Sarah A., Weiss, Kenneth M., Ritchie, Marylyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873241/
https://www.ncbi.nlm.nih.gov/pubmed/24385916
http://dx.doi.org/10.1371/journal.pgen.1003959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873241/
https://www.ncbi.nlm.nih.gov/pubmed/24385916
http://dx.doi.org/10.1371/journal.pgen.1003959

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