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Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

HoxA genes exhibit central roles during development and causal mutations have been found in several human syndromes including limb malformation. Despite their importance, information on how these genes are regulated is lacking. Here, we report on the first identification of bona fide transcriptional...

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Detalles Bibliográficos
Autores principales: Berlivet, Soizik, Paquette, Denis, Dumouchel, Annie, Langlais, David, Dostie, Josée, Kmita, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873244/
https://www.ncbi.nlm.nih.gov/pubmed/24385922
http://dx.doi.org/10.1371/journal.pgen.1004018