Quantifying Missing Heritability at Known GWAS Loci

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we...

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Detalles Bibliográficos
Autores principales: Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J., Diogo, Dorothée, Stahl, Eli A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M., Pasaniuc, Bogdan, Price, Alkes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873246/
https://www.ncbi.nlm.nih.gov/pubmed/24385918
http://dx.doi.org/10.1371/journal.pgen.1003993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873246/
https://www.ncbi.nlm.nih.gov/pubmed/24385918
http://dx.doi.org/10.1371/journal.pgen.1003993

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