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Smc5/6-Mms21 Prevents and Eliminates Inappropriate Recombination Intermediates in Meiosis

Repairing broken chromosomes via joint molecule (JM) intermediates is hazardous and therefore strictly controlled in most organisms. Also in budding yeast meiosis, where production of enough crossovers via JMs is imperative, only a subset of DNA breaks are repaired via JMs, closely regulated by the...

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Detalles Bibliográficos
Autores principales: Xaver, Martin, Huang, Lingzhi, Chen, Doris, Klein, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873250/
https://www.ncbi.nlm.nih.gov/pubmed/24385936
http://dx.doi.org/10.1371/journal.pgen.1004067