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Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by loss of neurons in the substantia nigra that project to the striatum and release dopamine. The cause of PD remains uncertain, however, evidence implicates mitochondrial dysfunction and oxidative stress. Although mos...

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Detalles Bibliográficos
Autores principales: Hennis, Meghan R., Seamans, Katherine W., Marvin, Marian A., Casey, Bradford H., Goldberg, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873453/
https://www.ncbi.nlm.nih.gov/pubmed/24386432
http://dx.doi.org/10.1371/journal.pone.0084894