Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

The role of sirtuin-1 (SIRT1) in innate immunity, and in particular the influence of SIRT1 on antimicrobial defense against infection, has yet to be reported but is important to define since SIRT1 inhibitors are being investigated as therapeutic agents in the treatment of cancer, Huntington’s diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: Crotty Alexander, Laura E., Marsh, Brenda J., Timmer, Anjuli M., Lin, Ann E., Zainabadi, Kayvan, Czopik, Agnieszka, Guarente, Leonard, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873454/
https://www.ncbi.nlm.nih.gov/pubmed/24386389
http://dx.doi.org/10.1371/journal.pone.0084481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873454/
https://www.ncbi.nlm.nih.gov/pubmed/24386389
http://dx.doi.org/10.1371/journal.pone.0084481

Ejemplares similares