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Gacyclidine improves the survival and reduces motor deficits in a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder typified by a massive loss of motor neurons with few therapeutic options. The exact cause of neuronal degeneration is unknown but it is now admitted that ALS is a multifactorial disease with several mechanisms involved includi...

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Detalles Bibliográficos
Autores principales: Gerber, Yannick N., Privat, Alain, Perrin, Florence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873512/
https://www.ncbi.nlm.nih.gov/pubmed/24409117
http://dx.doi.org/10.3389/fncel.2013.00280