Two Distinct Determinants of Ligand Specificity in T1R1/T1R3 (the Umami Taste Receptor)

Umami taste perception in mammals is mediated by a heteromeric complex of two G-protein-coupled receptors, T1R1 and T1R3. T1R1/T1R3 exhibits species-dependent differences in ligand specificity; human T1R1/T1R3 specifically responds to l-Glu, whereas mouse T1R1/T1R3 responds more strongly to other l-...

Descripción completa

Detalles Bibliográficos
Autores principales: Toda, Yasuka, Nakagita, Tomoya, Hayakawa, Takashi, Okada, Shinji, Narukawa, Masataka, Imai, Hiroo, Ishimaru, Yoshiro, Misaka, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873546/
https://www.ncbi.nlm.nih.gov/pubmed/24214976
http://dx.doi.org/10.1074/jbc.M113.494443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873546/
https://www.ncbi.nlm.nih.gov/pubmed/24214976
http://dx.doi.org/10.1074/jbc.M113.494443

Ejemplares similares