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Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption

Four hundred and seventy-two pasta samples were collected from long retail distribution chain sales points located in North, Central and South Italy. Representative criteria in the sample collection were followed in terms of number of samples collected, market share, and types of pasta. Samples were...

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Autores principales: Brera, Carlo, Bertazzoni, Valentina, Debegnach, Francesca, Gregori, Emanuela, Prantera, Elisabetta, De Santis, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873686/
https://www.ncbi.nlm.nih.gov/pubmed/24287568
http://dx.doi.org/10.3390/toxins5122293
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author Brera, Carlo
Bertazzoni, Valentina
Debegnach, Francesca
Gregori, Emanuela
Prantera, Elisabetta
De Santis, Barbara
author_facet Brera, Carlo
Bertazzoni, Valentina
Debegnach, Francesca
Gregori, Emanuela
Prantera, Elisabetta
De Santis, Barbara
author_sort Brera, Carlo
collection PubMed
description Four hundred and seventy-two pasta samples were collected from long retail distribution chain sales points located in North, Central and South Italy. Representative criteria in the sample collection were followed in terms of number of samples collected, market share, and types of pasta. Samples were analysed by an accredited HPLC-UV method of analysis. The mean contamination level (64.8 μg/kg) of deoxynivalenol (DON) was in the 95th percentile (239 μg/kg) and 99th percentile (337 μg/kg), far below the legal limit (750 μg/kg) set by Regulation EC/1126/2007, accounting for about one tenth, one third and half the legal limit, respectively. Ninety-nine percent of samples fell below half the legal limit. On the basis of the obtained occurrence levels and considering the consumption rates reported by the Italian official database, no health concern was assessed for all consumer groups, being that exposure was far below the Tolerable Daily Intake (TDI) of 1000 ng/kg b.w/day. Nevertheless, despite this, particular attention should be devoted to the exposure to DON by high consumers, such as children aged 3–5 years, who could reach the TDI even with very low levels of DON contamination.
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spelling pubmed-38736862013-12-27 Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption Brera, Carlo Bertazzoni, Valentina Debegnach, Francesca Gregori, Emanuela Prantera, Elisabetta De Santis, Barbara Toxins (Basel) Article Four hundred and seventy-two pasta samples were collected from long retail distribution chain sales points located in North, Central and South Italy. Representative criteria in the sample collection were followed in terms of number of samples collected, market share, and types of pasta. Samples were analysed by an accredited HPLC-UV method of analysis. The mean contamination level (64.8 μg/kg) of deoxynivalenol (DON) was in the 95th percentile (239 μg/kg) and 99th percentile (337 μg/kg), far below the legal limit (750 μg/kg) set by Regulation EC/1126/2007, accounting for about one tenth, one third and half the legal limit, respectively. Ninety-nine percent of samples fell below half the legal limit. On the basis of the obtained occurrence levels and considering the consumption rates reported by the Italian official database, no health concern was assessed for all consumer groups, being that exposure was far below the Tolerable Daily Intake (TDI) of 1000 ng/kg b.w/day. Nevertheless, despite this, particular attention should be devoted to the exposure to DON by high consumers, such as children aged 3–5 years, who could reach the TDI even with very low levels of DON contamination. MDPI 2013-11-26 /pmc/articles/PMC3873686/ /pubmed/24287568 http://dx.doi.org/10.3390/toxins5122293 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Brera, Carlo
Bertazzoni, Valentina
Debegnach, Francesca
Gregori, Emanuela
Prantera, Elisabetta
De Santis, Barbara
Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title_full Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title_fullStr Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title_full_unstemmed Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title_short Exposure Assessment for Italian Population Groups to Deoxynivalenol Deriving from Pasta Consumption
title_sort exposure assessment for italian population groups to deoxynivalenol deriving from pasta consumption
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873686/
https://www.ncbi.nlm.nih.gov/pubmed/24287568
http://dx.doi.org/10.3390/toxins5122293
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